Methylphosphonic dichloride
Names
[ CAS No. ]:
676-97-1
[ Name ]:
Methylphosphonic dichloride
[Synonym ]:
EINECS 211-634-4
Methanephosphonyl chloride
MFCD00002071
Methylphosphonyl dichloride
Methylphosphonicdichlorid
Phosphonic dichloride, P-methyl-
dichlorophosphorylmethane
Methyl phosphonyl dichloride
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
163.0±0.0 °C at 760 mmHg
[ Melting Point ]:
32-60ºC
[ Molecular Formula ]:
CH3Cl2OP
[ Molecular Weight ]:
132.914
[ Flash Point ]:
44.1±18.7 °C
[ Exact Mass ]:
131.929855
[ PSA ]:
26.88000
[ LogP ]:
0.25
[ Vapour Pressure ]:
2.8±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.420
[ Stability ]:
Stable, but may decompose in the presence of water or moisture. Incompatible with water, strong bases, strong oxidizing agents.
[ Water Solubility ]:
Soluble in water.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TA1840000
- CHEMICAL NAME :
- Phosphonic dichloride, methyl-
- CAS REGISTRY NUMBER :
- 676-97-1
- BEILSTEIN REFERENCE NO. :
- 1071305
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C-H3-Cl2-O-P
- MOLECULAR WEIGHT :
- 132.91
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 26 ppm/4H
- TOXIC EFFECTS :
- Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea Skin and Appendages - dermatitis, other (after systemic exposure)
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 25,470,1964
Safety Information
[ Symbol ]:
GHS05, GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314-H330
[ Supplemental HS ]:
Contact with water liberates toxic gas., Reacts violently with water.
[ Precautionary Statements ]:
P260-P280-P284-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T+
[ Risk Phrases ]:
R14;R26;R34
[ Safety Phrases ]:
S26-S28-S36/37/39-S45
[ RIDADR ]:
UN 3390 6
[ WGK Germany ]:
3
[ RTECS ]:
TA1840000
[ Packaging Group ]:
I
[ Hazard Class ]:
6.1
Precursor & DownStream
Precursor
DownStream
Articles
Biochemistry 32 , 10763, (1993)
Four phosphonamidates were synthesized as potential beta-lactamase inhibitors. Three were methanephosphonamidates [CH3PO2-NHR/Ar, where R/Ar = 4-methoxybenzyl (3a), phenyl (3b), and m-nitrophenyl (3c)...
Helv. Chim. Acta 75 , 2520, (1992)
Synth. Commun. 23 , 2273, (1993)