Nutlin-3b
Names
[ CAS No. ]:
675576-97-3
[ Name ]:
Nutlin-3b
[Synonym ]:
UNII-FJA1772CVW
nutlin-3B
4-({4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one
2-Piperazinone, 4-[[4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-
Piperazinone, 4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-, rel-;4-[4,5-Bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one
nutlin 3
4-{[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazol-1-yl]carbonyl}-2-piperazinone
NUTLIN 3B
Nutlin (3b)
Biological Activity
[Description]:
[Related Catalog]:
[Target]
IC50: 13.6 μM (MDM2/p53)
[In Vitro]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Molecular Formula ]:
C30H30Cl2N4O4
[ Molecular Weight ]:
581.490
[ Exact Mass ]:
580.164429
[ PSA ]:
86.96000
[ LogP ]:
2.77
[ Index of Refraction ]:
1.648
[ Storage condition ]:
-20℃