1-(4'-thio-beta-ribofuranosyl)thymine

Names

[ Name ]:
1-(4'-thio-beta-ribofuranosyl)thymine

[Synonym ]:
1-Ribo-4'-thiothymine
Uridine,5-methyl-4'-thio

Biological Activity

[Description]:

N6-Methyl-2-methyl thioadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀H₁₄N₂O₅S

[ Molecular Weight ]:
274.29

[ Exact Mass ]:
274.06200

[ PSA ]:
141.11000

1-(4'-thio-beta-ribofuranosyl)thymine

Names

Biological Activity

Chemical & Physical Properties

Related Compounds