ETHYLPHENACETIN
Names
[ CAS No. ]:
66922-67-6
[ Name ]:
ETHYLPHENACETIN
[Synonym ]:
Ethylphenacetin
p-ACETOPHENETIDIDE,N-ETHYL
N-Aethyl-phenacetin
Chemical & Physical Properties
[ Density]:
1.046g/cm3
[ Boiling Point ]:
324.3ºC at 760 mmHg
[ Molecular Formula ]:
C12H17NO2
[ Molecular Weight ]:
207.26900
[ Flash Point ]:
149.9ºC
[ Exact Mass ]:
207.12600
[ PSA ]:
29.54000
[ LogP ]:
2.45810
[ Index of Refraction ]:
1.529
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AM4400000
- CHEMICAL NAME :
- p-Acetophenetidide, N-ethyl-
- CAS REGISTRY NUMBER :
- 66922-67-6
- BEILSTEIN REFERENCE NO. :
- 3274909
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C12-H17-N-O2
- MOLECULAR WEIGHT :
- 207.30
- WISWESSER LINE NOTATION :
- 2OR DN2&V1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2500 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - acute pulmonary edema Blood - other changes
- REFERENCE :
- AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 33,216,1894
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 2700 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia Cardiac - other changes
- REFERENCE :
- AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 33,216,1894
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 3 gm/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Cardiac - pulse rate Cardiac - other changes
- REFERENCE :
- AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 33,216,1894