genistein 8-C-glucoside

Names

[ CAS No. ]:
66026-80-0

[ Name ]:
genistein 8-C-glucoside

[Synonym ]:
5,7-dihydroxy-3-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one
Genistein 8-C-glucoside

Biological Activity

[Description]:

Genistein 8-c-glucoside (G8CG) is a natural glucoside isolated from flowers of Lupinus luteus L. Genistein 8-c-glucoside induces mitochondrial membrane depolarization and induces apoptosis[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> Mitochondrial Metabolism

[References]

[1]. Antosiak A, et al. Cytotoxic activity of genistein-8-C-glucoside form Lupinus luteus L. and genistein against human SK-OV-3 ovarian carcinoma cell line. Med Chem Res. 2017;26(1):64-73.

Chemical & Physical Properties

[ Boiling Point ]:
767.7±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C21H20O10

[ Molecular Weight ]:
432.37800

[ Exact Mass ]:
432.10600

[ PSA ]:
181.05000

[ LogP ]:
0.09170

[ Storage condition ]:
2-8°C

Precursor & DownStream

Precursor

DownStream

Related Compounds