N-Dipropyldopamine hydrobromide

Names

[ Name ]:
N-Dipropyldopamine hydrobromide

[Synonym ]:
3,4-dihydroxy-N,N-di-(n-propyl)phenethylamine hydrobromide
N,N-Dipropyldopamine
N,N-di-n-propyldopamine hydrobromide
N,N-Dipropyldopamine hydrobromide
Dipropyldopamine hydrobromide
N,N-di-n-propyldopamine

Biological Activity

[Description]:

N. N-dipropyrldopamine is a potent inhibitor of glutamate release and has anticancer activity. The increase of glutamate secretion leads to cancer-induced bone pain (CIBP). N. N-dipropyrldopamine plays an analgesic role in CIBP[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[Target]

cystine/glutamate transporter (XC-)[1]IC50:25.45 μM (cystine/glutamate transporter, XC-)[1]

[References]

[1]. Fazzari J, et al. Inhibitors of glutamate release from breast cancer cells; new targets for cancer-induced bone-pain. Sci Rep. 2015 Feb 11;5:8380.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₂₄BrNO₂

[ Molecular Weight ]:
318.25

[ Exact Mass ]:
317.09900

[ PSA ]:
43.70000

[ LogP ]:
3.72040

Safety Information

[ WGK Germany ]:
3

[ RTECS ]:
RB5962000

[ HS Code ]:
2922299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922299090

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

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