H1-7 acetate salt

Names

[ Name ]:
H1-7 acetate salt

[Synonym ]:
HISTONE H1 PHOSPHORYLATION SITE
Histone-7
Cyclic-AMP dependent protein kinase substrate
ARG-ARG-LYS-ALA-SER-GLY-PRO
1-{2-[2-(2-{6-amino-2-[2-(2-amino-5-carbamimidamidopentanamido)-5-carbamimidamidopentanamido]hexanamido}propanamido)-3-hydroxypropanamido]acetyl}pyrrolidine-2-carboxylic acid
H1-7 (histone H1 phosphorylation site),PKA Substrate
Arg-Arg-Lys-Ala-Ser-Gly-Pro-OH
ARG-ARG-LYS-ALA-SER-GLY-PRO: RRKASGP
RRKASGP

Biological Activity

[Description]:

H1-7 (histone H1 phosphorylation site), PKA Substrate, a synthetic polypeptide, can be used as PKA substrate[1][2].

[Related Catalog]:

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PKA

Research Areas >> Others

Signaling Pathways >> Stem Cell/Wnt >> PKA

[In Vitro]

H1-7 (histone H1 phosphorylation site), PKA Substrate可用于检测 PKA 活性[2]。

[References]

[1]. Pomerantz AH, et, al. Studies on the mechanism of phosphorylation of synthetic polypeptides by a calf thymus cyclic AMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1977 Oct;74(10):4261-5.

[2]. Arif A, et, al. EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice. Nature. 2017 Feb 16;542(7641):357-361.

Chemical & Physical Properties

[ Density]:
1.54g/cm3

[ Molecular Formula ]:
C₃₁H₅₈N₁₄O₉

[ Molecular Weight ]:
770.88100

[ Exact Mass ]:
770.45100

[ PSA ]:
399.18000

[ Index of Refraction ]:
1.671

Related Compounds

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