Triflumuron

Names

[ Name ]:
Triflumuron

[Synonym ]:
1-(2-chlorobenzoyl)-3-(4-trifluoromethoxyphenyl)urea
Triflumuron
2-Chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide
2-chloro-N-[[[4-(trifluoromethoxy)phenyl]amino]carbonyl]benzamide
EINECS 264-980-3
Benzamide, 2-chloro-N-[[[4-(trifluoromethoxy)phenyl]amino]carbonyl]-
MFCD00072496
2-chloro-N-[[4-(trifluoromethoxy)phenyl]carbamoyl]benzamide

Biological Activity

[Description]:

Triflumuron is a potent chitin synthesis inhibitor. Triflumuron shows the efficacy in emergence inhibition (EI) against Culex quinquefasciatus and Aedes albopictus, with EI50 values of 5.28 and 1.59 μg/L, respectively. Triflumuron can be used as an insecticide. Triflumuron represents a potential tool for the control of disease vectors in public health[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[References]

[1]. Belinato TA,et al. Effect of triflumuron, a chitin synthesis inhibitor, on Aedes aegypti, Aedes albopictus and Culex quinquefasciatus under laboratory conditions. Parasit Vectors. 2013 Apr 4;6:83.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Melting Point ]:
188 - 190ºC

[ Molecular Formula ]:
C₁₅H₁₀ClF₃N₂O₃

[ Molecular Weight ]:
358.700

[ Exact Mass ]:
358.033203

[ PSA ]:
67.43000

[ LogP ]:
4.55

[ Index of Refraction ]:
1.582

[ Storage condition ]:
0-6°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CV2474000

CHEMICAL NAME :: Benzamide, 2-chloro-N-(((4-(trifluoromethoxy)phenyl)amino)carbon yl)-

CAS REGISTRY NUMBER :: 64628-44-0

LAST UPDATED :: 199612

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C15-H10-Cl-F3-N2-O3

MOLECULAR WEIGHT :: 358.72

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (47),3,1985

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >119 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ZANEAE Zeitschrift fuer Angewandte Entomologie. (Verlag Paul Parey, Postfach 106304, D-2000 Hamburg 1, Fed. Rep. Ger.) V.1-30, 1914-44; V.31- 1949- Volume(issue)/page/year: 89,289,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ZANEAE Zeitschrift fuer Angewandte Entomologie. (Verlag Paul Parey, Postfach 106304, D-2000 Hamburg 1, Fed. Rep. Ger.) V.1-30, 1914-44; V.31- 1949- Volume(issue)/page/year: 89,289,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ZANEAE Zeitschrift fuer Angewandte Entomologie. (Verlag Paul Parey, Postfach 106304, D-2000 Hamburg 1, Fed. Rep. Ger.) V.1-30, 1914-44; V.31- 1949- Volume(issue)/page/year: 89,289,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (47),3,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ZANEAE Zeitschrift fuer Angewandte Entomologie. (Verlag Paul Parey, Postfach 106304, D-2000 Hamburg 1, Fed. Rep. Ger.) V.1-30, 1914-44; V.31- 1949- Volume(issue)/page/year: 89,289,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ZANEAE Zeitschrift fuer Angewandte Entomologie. (Verlag Paul Parey, Postfach 106304, D-2000 Hamburg 1, Fed. Rep. Ger.) V.1-30, 1914-44; V.31- 1949- Volume(issue)/page/year: 89,289,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,850,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,850,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - domestic

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,850,1991

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H330

[ Precautionary Statements ]:
P260-P284-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
CV2474000

[ HS Code ]:
2924299037

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299037

[ Summary ]:
2924299037 2-chloro-n-((4-(trifluoromethoxy)phenyl)carbamoyl)benzamide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%

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