5-(2-Aminoethyl)-2-methoxyphenol hydrochloride

Names

[ CAS No. ]:
645-33-0

[ Name ]:
5-(2-Aminoethyl)-2-methoxyphenol hydrochloride

[Synonym ]:
5-(2-Aminoethyl)-2-methoxyphenol hydrochloride (1:1)
3-O-Methyldopamine hydrochloride
Homovanillylamine hydrochloride
4-O-Methyldopamine hydrochloride
Phenol, 4-(2-aminoethyl)-2-methoxy-, hydrochloride (1:1)
Phenol, 5-(2-aminoethyl)-2-methoxy-; hydrochloride (1:1)
Phenol, 5-(2-aminoethyl)-2-methoxy-, hydrochloride (1:1)
MFCD00012896
4-(2-Aminoethyl)-2-methoxyphenol hydrochloride (1:1)
EINECS 211-437-3
4-Methoxytyramine hydrochloride
5-(2-aminoethyl)-2-methoxyphenol,hydrochloride

Biological Activity

[Description]:

4-O-Methyldopamine hydrochloride is a catecholamine compound that has an inhibitory effect on dihydropteridine reductase[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. R S Shen, et al. Inhibition of dihydropteridine reductase by catecholamines and related compounds. Biochim Biophys Acta. 1983 Feb 28;743(1):129-35.

Chemical & Physical Properties

[ Boiling Point ]:
306.8ºC at 760 mmHg

[ Melting Point ]:
207-211 °C

[ Molecular Formula ]:
C₉H₁₄ClNO₂

[ Molecular Weight ]:
203.666

[ Flash Point ]:
139.3ºC

[ Exact Mass ]:
203.071304

[ PSA ]:
55.48000

[ LogP ]:
2.40430

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

The formation of 3-hydroxy-4-methoxyphenylalanine and 3-hydroxy-4-methoxyphenethylamine in plasma during L-DOPA therapy in patients with Parkinson's disease.

Chem. Pharm. Bull. 32(8) , 3320-2, (1984)

Efficient strategy for the selective determination of dopamine in human urine by molecularly imprinted solid-phase extraction.

J. Sep. Sci. 39 , 895-903, (2016)

An efficient molecularly imprinted solid-phase extraction protocol was developed for the separation of dopamine (DA) from human urine. After successful validation of the analytical method using high-p...

3-Hydroxy-4-methoxyphenethylamine, the cardioactive constituent of a soft coral.

Experientia 37(5) , 493-4, (1981)