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Acetaminophen-D4

Names

[ CAS No. ]:
64315-36-2

[ Name ]:
Acetaminophen-D4

[Synonym ]:
N-(2,3,5,6-tetradeuterio-4-hydroxyphenyl)acetamide

Chemical & Physical Properties

[ Melting Point ]:
169-171°C (dec.)

[ Molecular Formula ]:
C8H5D4NO2

[ Molecular Weight ]:
155.18700

[ Flash Point ]:
9℃

[ Exact Mass ]:
155.08800

[ PSA ]:
49.33000

[ LogP ]:
1.42360

[ Storage condition ]:
-20°C Freezer

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xn,T,F

[ Risk Phrases ]:
22-36/37/38-39/23/24/25-23/24/25-11

[ Safety Phrases ]:
26-36-45-36/37-16-7

[ RIDADR ]:
UN1230 - class 3 - PG 2 - Methanol, solution

Synthetic Route

Precursor & DownStream

Precursor

DownStream

Articles

In vitro metabolism and drug-drug interaction potential of UTL-5g, a novel chemo- and radioprotective agent.

Drug Metab. Dispos. 42(12) , 2058-67, (2014)

N-(2,4-dichlorophenyl)-5-methyl-1,2-oxazole-3-carboxamide (UTL-5g), a potential chemo- and radioprotective agent, acts as a prodrug requiring bioactivation to the active metabolite 5-methylisoxazole-3...

Upcyte Human Hepatocytes: a Potent In Vitro Tool for the Prediction of Hepatic Clearance of Metabolically Stable Compounds.

Drug Metab. Dispos. 44 , 435-44, (2016)

In vitro models based on primary human hepatocytes (PHH) have been advanced for clearance (CL) prediction of metabolically stable compounds, representing state-of-the-art assay systems for drug discov...

Cytochrome P450 induction response in tethered spheroids as a three-dimensional human hepatocyte in vitro model.

J. Appl. Toxicol. 36 , 320-9, (2016)

Cytochrome P450 (CYP) induction is a key risk factor of clinical drug-drug interactions that has to be mitigated in the early phases of drug discovery. Three-dimensional (3D) cultures of hepatocytes i...


More Articles


Related Compounds

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