aminometradine
Names
[ CAS No. ]:
642-44-4
[ Name ]:
aminometradine
[Synonym ]:
Aminometramide
Catapyrin
1-Allyl-6-amino-3-ethyl-2,4(1H,3H)-pyrimidinedione
Alacil
Aminometradinum [INN-Latin]
1-allyl-3-ethyl-6-aminouracil
6-amino-3-ethyl-1-(2-propenyl)-2,4(1H,3H)-pyrimidinedione
Mincard
3-ethyl-1-allyl-6-amino-1H-pyrimidine-2,4-dione
Mictine
AMINOMETRADINE
1-allyl-6-amino-3-ethyluracil
Allacyl
Katapyrin
3-Aethyl-1-allyl-6-amino-1H-pyrimidin-2,4-dion
Chemical & Physical Properties
[ Density]:
1.167g/cm3
[ Boiling Point ]:
292.8ºC at 760 mmHg
[ Molecular Formula ]:
C9H13N3O2
[ Molecular Weight ]:
195.21800
[ Flash Point ]:
130.9ºC
[ Exact Mass ]:
195.10100
[ PSA ]:
70.02000
[ LogP ]:
0.37930
[ Index of Refraction ]:
1.534
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YQ8665000
- CHEMICAL NAME :
- Uracil, 1-allyl-6-amino-3-ethyl-
- CAS REGISTRY NUMBER :
- 642-44-4
- BEILSTEIN REFERENCE NO. :
- 0175533
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C9-H13-N3-O2
- MOLECULAR WEIGHT :
- 195.25
- WISWESSER LINE NOTATION :
- T6NVNVJ A2U1 C2 FZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 14,392,1955
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PRPHA8 Produits Pharmaceutiques. (Paris, France) V.1-16, 1946-61. For publisher information, see PPRPAS. Volume(issue)/page/year: 13,125,1958
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 560 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PRPHA8 Produits Pharmaceutiques. (Paris, France) V.1-16, 1946-61. For publisher information, see PPRPAS. Volume(issue)/page/year: 13,125,1958