homatropine hydrochloride

Names

[ CAS No. ]:
637-21-8

[ Name ]:
homatropine hydrochloride

[Synonym ]:
HOMATROPINE HCL
AC1Q3EBX
DL-Mandelsaeure-tropan-3endo-ylester,Hydrochlorid
Homatropine hydrochloride
8-methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetatehydrochloride(1:1)
CTK8B4043
UNII-365MO3S3N9
DL-mandelic acid-tropane-3endo-ylester,hydrochloride
8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester,hydrochloride
EINECS 211-280-0
MFCD00050613
AC1L2STU

Biological Activity

[Description]:

Homatropine hydrochloride is an orally active anticholinergic agent that rapidly dilates pupils and has cycloplegic effects. Homatropine hydrochloride also has antitussive activity. Homatropine hydrochloride can be used in research on eye diseases and coughs[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> mAChR

Research Areas >> Others

Signaling Pathways >> GPCR/G Protein >> mAChR

[References]

[1]. Gore A, et al. Efficacy assessment of various anticholinergic agents against topical sarin-induced miosis and visual impairment in rats. Toxicol Sci. 2012 Apr;126(2):515-24.

Chemical & Physical Properties

[ Boiling Point ]:
403.3ºC at 760 mmHg

[ Melting Point ]:
226ºC

[ Molecular Formula ]:
C₁₆H₂₂ClNO₃

[ Molecular Weight ]:
311.80

[ Flash Point ]:
197.7ºC

[ Exact Mass ]:
311.12900

[ PSA ]:
49.77000

[ LogP ]:
2.62830

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xn

[ RIDADR ]:
UN 1544 6.1/PG 3

[ Packaging Group ]:
III

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%