Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate

Names

[ CAS No. ]:
632-93-9

[ Name ]:
Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate

[Synonym ]:
diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate
EINECS 211-188-0
3,5-Diethoxycarbonyl-1,4-dihydro-2,4,6-collidine
MFCD00005950

Biological Activity

[Description]:

Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate is a mouse-modeling drug that can induce Mallory body (MB) formation. MBs reached maximum concentration on day 5 of refeeding. Liver cell regeneration increased on the third day of refeeding[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Q X Yuan, et,al. Mallory body induction in drug-primed mouse liver. Hepatology. 1996, 24, 3.

Chemical & Physical Properties

[ Density]:
1.12g/cm3

[ Boiling Point ]:
335ºC at 760 mmHg

[ Melting Point ]:
130-132 °C(lit.)

[ Molecular Formula ]:
C₁₄H₂₁NO₄

[ Molecular Weight ]:
267.32

[ Flash Point ]:
123.3ºC

[ Exact Mass ]:
267.14700

[ PSA ]:
64.63000

[ LogP ]:
2.22870

[ Index of Refraction ]:
1.51

[ Storage condition ]:
Flammables area

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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