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TUG-1387

Names

[ CAS No. ]:
6319-64-8

[ Name ]:
TUG-1387

[Synonym ]:
4-methyl-N-9H-xanthen-9-yl-Benzamide
N-xanthen-9-yl-p-toluamide
N-(9-Xanthyl)-p-toluamid

Biological Activity

[Description]:

TUG-1387 is a analog of both AH-7614 and TUG-1506 that has no activity at FFA4. TUG-1387 can serve as negative control for studies assessing FFA4 function.

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Watterson KR, et al. Probe-Dependent Negative Allosteric Modulators of the Long-Chain Free Fatty Acid Receptor FFA4. Mol Pharmacol. 2017 Jun;91(6):630-641.

[2]. Milligan G, et al. FFA4/GPR120: Pharmacology and Therapeutic Opportunities. Trends Pharmacol Sci. 2017 Sep;38(9):809-821.

Chemical & Physical Properties

[ Density]:
1.25g/cm3

[ Boiling Point ]:
503.9ºC at 760 mmHg

[ Molecular Formula ]:
C21H17NO2

[ Molecular Weight ]:
315.36500

[ Flash Point ]:
258.6ºC

[ Exact Mass ]:
315.12600

[ PSA ]:
38.33000

[ LogP ]:
5.01100

[ Index of Refraction ]:
1.669

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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