Methyl methoxyacetate

Names

[ CAS No. ]:
6290-49-9

[ Name ]:
Methyl methoxyacetate

[Synonym ]:
Acetic acid, 2-methoxy-, methyl ester
Methyl methoxyacetate
EINECS 228-539-9
MFCD00008451

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
131.0±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₄H₈O₃

[ Molecular Weight ]:
104.104

[ Flash Point ]:
34.1±11.4 °C

[ Exact Mass ]:
104.047340

[ PSA ]:
35.53000

[ LogP ]:
0.01

[ Vapour Pressure ]:
9.5±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.379

[ Storage condition ]:
Flammables area

[ Water Solubility ]:
soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AI8910000

CHEMICAL NAME :: Acetic acid, methoxy-, methyl ester

CAS REGISTRY NUMBER :: 6290-49-9

BEILSTEIN REFERENCE NO. :: 1742944

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C4-H8-O3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LC - Lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg/10M

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NDRC** National Defense Research Committee, Office of Scientific Research and Development, Progress Report. Volume(issue)/page/year: NDCrc-132,Feb,1942

Safety Information

[ Symbol ]:

GHS02

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R10

[ Safety Phrases ]:
S16-S29-S33

[ RIDADR ]:
UN 3272 3/PG 3

[ WGK Germany ]:
2

[ RTECS ]:
AI8910000

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
29189090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Predicting and avoiding subcellular compartmentalization artifacts arising from acetoxymethyl ester calcium imaging probes. The case of fluo-3 AM and a general account of the phenomenon including a problem avoidance chart.

Biotech. Histochem. 87(7) , 468-83, (2012)

Stimulated by difficulties experienced when using fluo-3 AM, we developed a general mechanistic model to aid understanding and practical application of calcium probes applied as acetoxymethyl (AM) est...

[Information from the Soviet Toxicology Center].

Farmakol. Toksikol. 43(6) , 750-1, (1980)

Regional difference in stainability with calcium-sensitive acetoxymethyl-ester probes in mouse brain slices.

Int. J. Neurosci. 119(2) , 214-26, (2009)

Loading neurons with membrane permeable Ca2+ indicators is a core experimental procedure in functional multineuron Ca2+ imaging (fMCI), an optical technique for monitoring multiple neuronal activities...