DOTA-NOC

Names

[ CAS No. ]:
619300-53-7

[ Name ]:
DOTA-NOC

Biological Activity

[Description]:

DOTA-NOC (DOTA-Nal3-octreotide) is a high-affinity ligand of somatostatin receptor subtypes 2, 3 and 5. DOTA-NOC can be used for labeling with various radiometals, and development of radiopeptide imaging[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Somatostatin Receptor

Research Areas >> Others

[In Vitro]

结合人生长抑素受体 SST 1-5 的亲和力数据 (IC50(μM))[1]. Compound hsst1 hsst2 hsst3 hsst4 hsst5 InIII-DOTA-NOC >10000 2.9 8 227 11.2 YIII-DOTA-NOC >10000 3.3 26 >10000 10.4

[References]

[1]. Wild D, et al. DOTA-NOC, a high-affinity ligand of somatostatin receptor subtypes 2, 3 and 5 for labelling with various radiometals. Eur J Nucl Med Mol Imaging. 2003 Oct;30(10):1338-47.

Chemical & Physical Properties

[ Molecular Formula ]:
C₆₉H₉₄N₁₄O₁₇S₂

Related Compounds

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