Pirlindole. Lifril

Names

[ Name ]:
Pirlindole. Lifril

[Synonym ]:
Pirlindole mesylate

Biological Activity

[Description]:

Pirlindole is a selective and reversible MAO-A inhibitor[1]. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3)[2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase

Research Areas >> Neurological Disease

[References]

[1]. Bruhwyler J, et al. Pirlindole: a selective reversible inhibitor of monoamine oxidase A. A review of its preclinical properties. Pharmacol Res. 1997 Jul;36(1):23-33.

[2]. Ulferts R, et al. Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C. Antimicrob Agents Chemother. 2016 Apr 22;60(5):2627-38.

Chemical & Physical Properties

[ Density]:
1.29 g/cm3

[ Boiling Point ]:
422.6ºC at 760 mmHg

[ Molecular Formula ]:
C₁₆H₂₂N₂O₃S

[ Molecular Weight ]:
322.42200

[ Flash Point ]:
209.4ºC

[ Exact Mass ]:
322.13500

[ PSA ]:
79.71000

[ LogP ]:
3.84390

Safety Information

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%