Glabrone

Names

[ Name ]:
Glabrone

[Synonym ]:
7,5'-dihydroxy-2',2'-dimethyl-2'H-[3,6']bichromenyl-4-one
Morusin hydroperoxide
4H-1-Benzopyran-4-one,7-hydroxy-3-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)
Glabrone
HMS2268B14

Biological Activity

[Description]:

Glabrone is an isoflavone isolated from Glycyrrhiza glabra roots. Glabrone exhibits anti-influenza activity and significant PPAR-γ ligand-binding activity[1][2].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR

Research Areas >> Metabolic Disease

[Target]

PPAR-γ

[References]

[1]. Grienke U, et al. Computer-guided approach to access the anti-influenza activity of licorice constituents. J Nat Prod. 2014 Mar 28;77(3):563-70.

[2]. Kuroda M, et al. Phenolics from Glycyrrhiza glabra roots and their PPAR-gamma ligand-binding activity. Bioorg Med Chem. 2010 Jan 15;18(2):962-70.

Chemical & Physical Properties

[ Density]:
1.368g/cm3

[ Boiling Point ]:
554.1ºC at 760 mmHg

[ Molecular Formula ]:
C₂₀H₁₆O₅

[ Molecular Weight ]:
336.33800

[ Flash Point ]:
202.6ºC

[ Exact Mass ]:
336.10000

[ PSA ]:
79.90000

[ LogP ]:
4.05540

[ Index of Refraction ]:
1.659

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2914400090

Customs

[ HS Code ]: 2914400090

[ Summary ]:
2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%