1-(2,3,5-Tribenzoyl--D-ribofuranosyl)-5-nitropyridine-2(1H)-one

Names

[ Name ]:
1-(2,3,5-Tribenzoyl--D-ribofuranosyl)-5-nitropyridine-2(1H)-one

[Synonym ]:
1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-5-nitropyridine-2(1H)-one
5-nitro-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2-pyridone

Biological Activity

[Description]:

5-Nitro-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyridinone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₁H₂₄N₂O₁₀

[ Molecular Weight ]:
584.53

[ Exact Mass ]:
584.14300

[ PSA ]:
155.95000

[ LogP ]:
4.48530

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.