(Leu13)-Motilin (human, porcine) trifluoroacetate salt

Names

[ Name ]:
(Leu13)-Motilin (human, porcine) trifluoroacetate salt

[Synonym ]:
kw 5139
(Leu13)-Motilin
[Leu13]-Motilin

Biological Activity

[Description]:

[Leu13]-Motilin (KW-5139) is a motilin analogue. [Leu13]-Motilin stimulates gastrointestinal motility in the rabbit. [Leu13]-Motilin causes concentration-dependent contractions of the gastric antrum, duodenum, jejunum, ileum and the descending colon in vitro[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

Signaling Pathways >> GPCR/G Protein >> Motilin Receptor

[References]

[1]. Kitazawa T, et al. Stimulating action of KW-5139 (Leu13-motilin) on gastrointestinal motility in the rabbit. Br J Pharmacol. 1994 Jan;111(1):288-94.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂₁H₁₉₀N₃₄O₃₅

[ Molecular Weight ]:
2681.01

[ Exact Mass ]:
2679.41000

[ PSA ]:
1166.19000

[ LogP ]:
5.04760

Related Compounds

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