L-Histidine hydrochloride monohydrate

Names

[ Name ]:
L-Histidine hydrochloride monohydrate

[Synonym ]:
MFCD00151027
l-histidine mono hydrochloride monohydrate
EINECS 211-438-9
Histidine hydrochloride hydrate
(2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid hydrate hydrochloride
L-histidine, hydrochloride, hydrate
L-histidine, monohydrochloride, monohydrate
Histidine, hydrochloride, hydrate (1:1:1)
(2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid,hydrate,hydrochloride
(S)-2-Amino-3-(1H-imidazol-4-yl)propanoic acid hydrochloride hydrate
L-HISTIDINE monohydrochloride MONOHYDRATE
L-Histidine Hydrochloride Monohydrate

Chemical & Physical Properties

[ Density]:
1.485 g/cm3

[ Boiling Point ]:
458.9ºC at 760 mmHg

[ Melting Point ]:
254 °C (dec.)(lit.)

[ Molecular Formula ]:
C₆H₁₂ClN₃O₃

[ Molecular Weight ]:
209.631

[ Flash Point ]:
231.3ºC

[ Exact Mass ]:
209.056717

[ PSA ]:
101.23000

[ LogP ]:
0.80210

[ Water Solubility ]:
169.9 g/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MS3119000

CHEMICAL NAME :: Histidine, monohydrochloride, monohydrate, L-

CAS REGISTRY NUMBER :: 5934-29-2

LAST UPDATED :: 199504

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C6-H9-N3-O2.Cl-H.H2-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1677 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 97,1117,1977 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9996 No. of Facilities: 148 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 512 (estimated) No. of Female Employees: 187 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
MS3119000

[ HS Code ]:
29332990

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 29332990

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