Cyclizine dihydrochloride
Names
[ CAS No. ]:
5897-18-7
[ Name ]:
Cyclizine dihydrochloride
[Synonym ]:
Cyclizine dihydrochloride
Cyclizine 2HCl
Chemical & Physical Properties
[ Molecular Formula ]:
C18H23ClN2
[ Molecular Weight ]:
302.84200
[ Exact Mass ]:
302.15500
[ PSA ]:
6.48000
[ LogP ]:
3.70120
[ Storage condition ]:
-20℃
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TL6490000
- CHEMICAL NAME :
- Piperazine, 1-diphenylmethyl-4-methyl-, dihydrochloride
- CAS REGISTRY NUMBER :
- 5897-18-7
- LAST UPDATED :
- 199606
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C18-H22-N2.2Cl-H
- MOLECULAR WEIGHT :
- 339.34
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 69 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - excitement Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 46,279,1957 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 11928 mg/kg/12W-C
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - chronic pulmonary edema Liver - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 112,297,1954
Related Compounds
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.