EMA [Ethidium monoazide bromide]

Names

[ CAS No. ]:
58880-05-0

[ Name ]:
EMA [Ethidium monoazide bromide]

[Synonym ]:
Phenanthridinium,3-amino-8-azido-5-ethyl-6-phenyl-,bromide
MFCD00213986
3-Amino-8-azido-5-ethyl-6-phenylphenanthridinium bromide
Ethidium azide bromide
Ethidium bromide monoazide
Ethidium monoazide bromide
Monoazido ethidium bromide

Biological Activity

[Description]:

Ethidium monoazide bromide is a DNA intercalating fluorescent dye that enters bacteria with damaged membranes. Ethidium monoazide bromide can be covalently linked to DNA by photoactivation. Ethidium monoazide bromide stains only dead cells[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Nogva HK, et al. Ethidium monoazide for DNA-based differentiation of viable and dead bacteria by 5'-nuclease PCR. Biotechniques. 2003 Apr;34(4):804-8, 810, 812-3.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H18BrN5

[ Molecular Weight ]:
420.30500

[ Exact Mass ]:
419.07500

[ PSA ]:
79.65000

[ LogP ]:
2.52936

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SF7941850
CHEMICAL NAME :
Phenanthridinium, 3-amino-8-azido-5-ethyl-6-phenyl-, bromide
CAS REGISTRY NUMBER :
58880-05-0
LAST UPDATED :
199707
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C21-H18-N5.Br
MOLECULAR WEIGHT :
420.35
WISWESSER LINE NOTATION :
T B666 HKJ EZ H2 IR& LNNN &E

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Yeast - Saccharomyces cerevisiae
DOSE/DURATION :
2 umol/L/30M
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 56,21,1977

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
SF7941850

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