Platycodin D

Names

[ Name ]:
Platycodin D

[Synonym ]:
α-L-Arabinopyranose, O-3-O-[(2S,3R,4R)-tetrahydro-3,4-dihydroxy-4-(hydroxymethyl)-2-furanyl]-β-D-xylopyranosyl-(1->4)-O-6-deoxy-α-L-mannopyranosyl-(1->2)-1-O-[(2β,3β,16α)-3-(β- 
D-glucopyranosyloxy)-2,16,23,24-tetrahydroxy-28-oxoolean-12-en-28-yl]-
PlatycodinD
Platycodin
3-O-[(2S,3R,4R)-3,4-Dihydroxy-4-(hydroxymethyl)tetrahydro-2-furanyl]-β-D-xylopyranosyl-(1->4)-6-deoxy-α-L-mannopyranosyl-(1->2)-1-O-[(2β,3β,16α)-3-(β-D-glucopyranosyloxy)-2,16,23,2 ; 4-tetrahydroxy-28-oxoolean-12-en-28-yl]-α-L-arabinopyranose

Biological Activity

[Description]:

Platycodin D is a saponin isolated from Platycodi Radix, acts as an activator of AMPKα, with anti-obesity property[1].

[Related Catalog]:

Signaling Pathways >> Epigenetics >> AMPK

Signaling Pathways >> PI3K/Akt/mTOR >> AMPK

Research Areas >> Metabolic Disease

[Target]

AMPKα[1]

[References]

[1]. Kim HL, et al. Platycodin D, a novel activator of AMP-activated protein kinase, attenuates obesity in db/db mice via regulation of adipogenesis and thermogenesis. Phytomedicine. 2019 Jan;52:254-263.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Molecular Formula ]:
C₅₇H₉₂O₂₈

[ Molecular Weight ]:
1225.324

[ Exact Mass ]:
1224.577515

[ PSA ]:
453.28000

[ LogP ]:
-0.69

[ Index of Refraction ]:
1.659

[ Storage condition ]:
2~8°C

Safety Information

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
RK0177962

Precursor & DownStream

Precursor

DownStream

Related Compounds

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