1-Bromo-2,4-dinitrobenzene

Names

[ CAS No. ]:
584-48-5

[ Name ]:
1-Bromo-2,4-dinitrobenzene

[Synonym ]:
EINECS 209-539-8
2,4-dinitro-1-bromobenzene
DNBB
1-BROMO-2,4-DINITROBENZENE
1-bromo 2,4-dinitrobenzene
2-bromo-1,5-dinitrobenzene
2,4-Dinitrophenyl bromide
4-Bromo-1,3-dinitrobenzene
1-Bromo-2,4-dinitrobenze
2,4-Dinitrobromobenzene
o,p-Dinitrophenyl bromide
BENZENE,1-BROMO-2,4-DINITRO
MFCD00041873

Chemical & Physical Properties

[ Density]:
1.91g/cm3

[ Boiling Point ]:
288.4ºC at 760 mmHg

[ Melting Point ]:
71-73 °C(lit.)

[ Molecular Formula ]:
C₆H₃BrN₂O₄

[ Molecular Weight ]:
247.00300

[ Flash Point ]:
128.2ºC

[ Exact Mass ]:
245.92800

[ PSA ]:
91.64000

[ LogP ]:
3.31190

[ Index of Refraction ]:
1.647

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CY9021500

CHEMICAL NAME :: Benzene, 1-bromo-2,4-dinitro-

CAS REGISTRY NUMBER :: 584-48-5

LAST UPDATED :: 199709

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C6-H3-Br-N2-O4

MOLECULAR WEIGHT :: 247.02

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 5 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 176,171,1987

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H317-H319

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38-43

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
UN3459

[ WGK Germany ]:
3

[ RTECS ]:
CY9021500

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2904909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2904909090

[ Summary ]:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Glutathione metabolism in the HaCaT cell line as a model for the detoxification of the model sensitisers 2,4-dinitrohalobenzenes in human skin.

Toxicol. Lett. 237 , 11-20, (2015)

Glutathione (GSH) is the most prominent antioxidant in cells and the co-factor of an important set of enzymes involved in the skin metabolic clearance system, glutathione S-transferases (GST). Here, w...

Time dependence in mixture toxicity with soft electrophiles: 1. Combined effects of selected SN2- and SNAr-reactive agents with a nonpolar narcotic.

Arch. Environ. Contam. Toxicol. 52(3) , 283-93, (2007)

Frequently the toxicity of an organic chemical mixture is close to dose-additive, even when the agents are thought to induce toxicity at different molecular sites of action. These findings appear to c...

Sequence, catalytic properties and expression of chicken glutathione-dependent prostaglandin D2 synthase, a novel class Sigma glutathione S-transferase.

Biochem. J. 333 , 317-25, (1998)

The Expressed Sequence Tag database has been screened for cDNA clones encoding prostaglandin D2 synthases (PGDSs) by using a BLAST search with the N-terminal amino acid sequence of rat GSH-dependent P...