Isoserine

Names

[ CAS No. ]:
565-71-9

[ Name ]:
Isoserine

[Synonym ]:
3-Aminolactic acid
MFCD00008138
5-Oxo-L-proline 1-methylethyl ester
(DL)-3-Amino-2-hydroxypropanoic Acid
L-Pyroglutamic acid isopropyl ester
isopropyl 5-oxo-L-prolinate
3-Amino-2-hydroxypropanoic acid
Isoserine
Propanoic acid, 3-amino-2-hydroxy-
pyroglutamic acid iso-propyl ester
3-Amino-2-hydroxypropionic acid

Biological Activity

[Description]:

3-Amino-2-hydroxypropanoic acid is a serine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
386.6±27.0 °C at 760 mmHg

[ Melting Point ]:
235ºC (dec.)

[ Molecular Formula ]:
C₃H₇NO₃

[ Molecular Weight ]:
105.093

[ Flash Point ]:
187.6±23.7 °C

[ Exact Mass ]:
105.042595

[ PSA ]:
83.55000

[ LogP ]:
-0.97

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.519

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Novel parent structures for inhibitors of the murine GABA transporters mGAT3 and mGAT4.

Eur. J. Pharmacol. 519(1-2) , 43-7, (2005)

Searching for potent and subtype selective parent structures of the murine gamma-aminobutyric acid (GABA) transporter subtypes mGAT3 and mGAT4 a series of amino acids was characterised in a uniform [3...

Glycine conjugates in a lepidopteran insect herbivore--the metabolism of benzylglucosinolate in the cabbage white butterfly, Pieris rapae.

ChemBioChem. 7(12) , 1982-9, (2006)

Herbivores have developed a wide array of countermeasures to overcome plants' chemical defences. Larvae of the cabbage white butterfly, Pieris rapae, feed exclusively on plants of the Brassicales orde...

Microbial resolution of 2-hydroxy-3-nitropropionic acid for synthesis of optically active isoserine.

Biosci. Biotechnol. Biochem. 65(5) , 1258-60, (2001)

The biocatalytic stereoselective hydrolysis of 2-hydroxy-3-nitropropionic acid esters was studied. Forty enzymes and three hundred microorganism strains were examined for their ability to hydrolyze et...