Thiol-C2-PEG2-OH
Names
[ CAS No. ]:
56282-36-1
[ Name ]:
Thiol-C2-PEG2-OH
[Synonym ]:
2-[2-(2-sulfanylethoxy)ethoxy]ethanol
Biological Activity
[Description]:
Thiol-C2-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[Related Catalog]:
[Target]
PEGs
[In Vitro]
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]
[References]
Chemical & Physical Properties
[ Density]:
1.094g/cm3
[ Boiling Point ]:
270.3ºC at 760 mmHg
[ Molecular Formula ]:
C6H14O3S
[ Molecular Weight ]:
166.23900
[ Flash Point ]:
117.3ºC
[ Exact Mass ]:
166.06600
[ PSA ]:
77.49000
[ Index of Refraction ]:
1.475