Altertoxin I

Names

[ Name ]:
Altertoxin I

[Synonym ]:
altertoxin I
3,6a,7,10-tetrahydroxy-4,9-dioxo-4,5,6,6a,6b,7,8,9-octahydroperylene
ALTERTOXIN I

Biological Activity

[Description]:

Altertoxin I (Dihydroalterperylenol) is a quinone-type mycotoxin produced by Alternaria alternata fungi, which is mutagenic and cytotoxic, and can weakly disrupts metabolic communication[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Jarolim K, et al. Activation of the Nrf2-ARE pathway by the Alternaria alternata mycotoxins altertoxin I and II. Arch Toxicol. 2017 Jan;91(1):203-216.

[2]. Boutin BK, et al. Effects of purified altertoxins I, II, and III in the metabolic communication V79 system. J Toxicol Environ Health. 1989;26(1):75-81.

[3]. Stack ME, et al. Mutagenicity of the Alternaria metabolites altertoxins I, II, and III. Appl Environ Microbiol. 1986 Oct;52(4):718-22.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₁₆O₆

[ Molecular Weight ]:
352.33700

[ Exact Mass ]:
352.09500

[ PSA ]:
115.06000

[ LogP ]:
1.97340

Related Compounds

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