Isobutylene Oxide

Names

[ CAS No. ]:
558-30-5

[ Name ]:
Isobutylene Oxide

[Synonym ]:
2,2-dimethyloxirane
MFCD00066354
EINECS 209-193-8

Chemical & Physical Properties

[ Density]:
0.812 g/mL at 25 °C(lit.)

[ Boiling Point ]:
50-51 °C(lit.)

[ Molecular Formula ]:
C₄H₈O

[ Molecular Weight ]:
72.10570

[ Flash Point ]:
33 °F

[ Exact Mass ]:
72.05750

[ PSA ]:
12.53000

[ LogP ]:
0.79520

[ Index of Refraction ]:
n20/D 1.374(lit.)

[ Storage condition ]:
Flammables area

[ Water Solubility ]:
58 g/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TZ3580000

CHEMICAL NAME :: Propane, 1,2-epoxy-2-methyl-

CAS REGISTRY NUMBER :: 558-30-5

BEILSTEIN REFERENCE NO. :: 0102408

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C4-H8-O

MOLECULAR WEIGHT :: 72.12

WISWESSER LINE NOTATION :: T3OTJ B1 B1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Klebsiella pneumoniae

DOSE/DURATION :: 5 mmol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 89,269,1981

Safety Information

[ Symbol ]:

GHS02, GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H314-H335

[ Precautionary Statements ]:
P210-P261-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
F:Flammable;Xn:Harmful;

[ Risk Phrases ]:
R11;R20/21/22;R36/37/38

[ Safety Phrases ]:
S16-S26-S36-S36/37/39

[ RIDADR ]:
UN 1993 3/PG 1

[ WGK Germany ]:
2

[ RTECS ]:
TZ3580000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
29109000

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 29109000

Articles

Mutagenicity of 2-methylpropene (isobutene) and its epoxide in a modified Salmonella assay for volatile compounds.

Mutat. Res. 271(3) , 213-21, (1992)

The mutagenic properties of 2-methylpropene (MP) and 2-methyl-1,2- epoxypropane (MEP) were investigated in the Salmonella assay. A simple exposure system, consisting of gastight tissue culture flasks,...

Comparative mutagenicity of 2-methylpropene (isobutene), its epoxide 2-methyl-1,2-epoxypropane and propylene oxide in the in vitro micronucleus test using human lymphocytes.

Mutagenesis 10(2) , 101-4, (1995)

2-Methylpropene (isobutene), a gaseous compound widely used in chemical industries, is metabolized to the epoxide 2-methyl-1,2-epoxypropane. The parent compound has previously been shown to be non-mut...

In vitro biotransformation of 2-methylpropene (isobutene): epoxide formation in mice liver.

Arch. Toxicol. 65(4) , 263-7, (1991)

Until now, no data are available concerning the biotransformation and toxicity of 2-methylpropene (or isobutene), a gaseous alkene widely used in industry (rubber, fuel additives, plastic polymers, ad...