Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside [Quercetin-3-O-(2G-alpha-L-rhamnosyl)-rutinoside]

Names

[ Name ]:
Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside [Quercetin-3-O-(2G-alpha-L-rhamnosyl)-rutinoside]

Biological Activity

[Description]:

Manghaslin is a flavonoid glycoside with anti-inflammatory activities. Manghaslin shows inhibitory activity against AChE with an IC50 of 94.92 µM[1][2].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Neuronal Signaling >> AChE

[In Vitro]

Manghaslin reduces the release of NO in LPS-stimulated macrophages. Manghaslin also decreases the levels of TNF-α and Neopterin[1].

[References]

[1]. Hasan Kırmızıbekmez, et al. Phenolic compounds from the aerial parts of Clematis viticella L. and their in vitro anti-inflammatory activities. Nat Prod Res. 2019 Sep;33(17):2541-2544.

[2]. Daniil N Olennikov, et al. Isorhamnetin and Quercetin Derivatives as Anti-Acetylcholinesterase Principles of Marigold (Calendula officinalis) Flowers and Preparations. Int J Mol Sci. 2017 Aug 2;18(8):1685.

Chemical & Physical Properties

[ Density]:
1.79±0.1 g/cm3(Predicted)

[ Boiling Point ]:
1090.4±65.0 °C(Predicted)

[ Melting Point ]:
168-170 °C

[ Molecular Formula ]:
C₃₃H₄₀O₂₀

[ Molecular Weight ]:
756.7

[ Exact Mass ]:
756.211294