1H-Benz[de]isoquinoline-1,3(2H)-dione,5-nitro-2-[2-(1-pyrrolidinyl)ethyl]-
Names
[ CAS No. ]:
54824-20-3
[ Name ]:
1H-Benz[de]isoquinoline-1,3(2H)-dione,5-nitro-2-[2-(1-pyrrolidinyl)ethyl]-
[Synonym ]:
1H-Benz[de]isoquinoline-1,5-nitro-2-[2-(1-pyrrolidinyl)ethyl]
Pinafide
Chemical & Physical Properties
[ Density]:
1.402g/cm3
[ Boiling Point ]:
548ºC at 760 mmHg
[ Molecular Formula ]:
C18H17N3O4
[ Molecular Weight ]:
339.34500
[ Flash Point ]:
285.2ºC
[ Exact Mass ]:
339.12200
[ PSA ]:
88.13000
[ LogP ]:
2.41780
[ Index of Refraction ]:
1.679
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QK5980000
- CHEMICAL NAME :
- Naphthalimide, 2-(2-(pyrrolidinyl)ethyl)-5-nitro-
- CAS REGISTRY NUMBER :
- 54824-20-3
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C18-H17-N3-O4
- MOLECULAR WEIGHT :
- 339.38
- WISWESSER LINE NOTATION :
- T666 1A M CVNVJ D2- AT5NTJ& HNW
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4500 ug/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 12600 ug/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Rodent - mouse Ascites tumor
- DOSE/DURATION :
- 3 mg/L
- REFERENCE :
- CCPHDZ Cancer Chemotherapy and Pharmacology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1978- Volume(issue)/page/year: 4,61,1980
Safety Information
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%