Basic Orange 2
Names
[ CAS No. ]:
532-82-1
[ Name ]:
Basic Orange 2
[Synonym ]:
Chrysoidin
EINECS 208-545-8
Chrysoidine ygh
4-Phenylazo-m-phenylenediamine monohydrochloride,Basic Orange 2,Chrysoidine Y
Chrysoidine Y
4-[(Z)-Phenyldiazenyl]-1,3-benzenediamine hydrochloride (1:1)
2,4-diaminoazobenzene hydrochloride
4-[(Z)-phenyldiazenyl]benzene-1,3-diamine hydrochloride
4-phenylazo-m-phenylenediamine,hydrochloride
1,3-benzenediamine, 4-[(Z)-phenylazo]-, monohydrochloride
Basic orange 2 (C.I. 11270)
Chrysoidine A
2,4-diaminophenylazobenzene hydrochloride
Chrysoidine B
chrysoidine hydrochloride
MFCD00012976
Chrysoidine J
Chrysoidine G
Chrysoidine
Basic Orange 2
1,3-Benzenediamine, 4-[(Z)-2-phenyldiazenyl]-, hydrochloride (1:1)
C.I. BASIC ORANGE 2
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Boiling Point ]:
454ºC at 760 mmHg
[ Melting Point ]:
235 °C (dec.)(lit.)
[ Molecular Formula ]:
C12H13ClN4
[ Molecular Weight ]:
248.711
[ Flash Point ]:
228.4ºC
[ Exact Mass ]:
248.082870
[ PSA ]:
76.76000
[ LogP ]:
5.23080
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- ST3380000
- CHEMICAL NAME :
- m-Phenylenediamine, 4-(phenylazo)-, hydrochloride
- CAS REGISTRY NUMBER :
- 532-82-1
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 15
- MOLECULAR FORMULA :
- C12-H12-N4.Cl-H
- MOLECULAR WEIGHT :
- 248.74
- WISWESSER LINE NOTATION :
- ZR CZ DNUNR &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6670 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - muscle weakness Gastrointestinal - nausea or vomiting
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5153 mg/kg/17W-I
- TOXIC EFFECTS :
- Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - catalases
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 93600 mg/kg/56W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 94 gm/kg/57W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Yeast - Saccharomyces cerevisiae
- DOSE/DURATION :
- 100 ug/L
- REFERENCE :
- VINIT* Vsesoyuznyi Institut Nauchnoi i Tekhnicheskoi Informatsii (VINITI). All-Union Institute of Scientific and Technical Information. (Moscow, USSR) Use information broker to obtain publications. Volume(issue)/page/year: #428-84 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,91,1975 IARC Cancer Review:Human Inadequate Evidence IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,169,1987 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,169,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M2097 No. of Facilities: 291 (estimated) No. of Industries: 7 No. of Occupations: 13 No. of Employees: 3278 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M2097 No. of Facilities: 315 (estimated) No. of Industries: 7 No. of Occupations: 14 No. of Employees: 6996 (estimated) No. of Female Employees: 2725 (estimated)
Safety Information
[ Symbol ]:
GHS05, GHS07, GHS08, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H315-H318-H341-H410
[ Precautionary Statements ]:
P273-P280-P305 + P351 + P338-P501
[ Personal Protective Equipment ]:
Gloves
[ Hazard Codes ]:
N:Dangerousfortheenvironment;
[ Risk Phrases ]:
R50/53
[ Safety Phrases ]:
S60-S61
[ RIDADR ]:
UN 3077 9/PG 3
[ WGK Germany ]:
2
[ RTECS ]:
ST3380000
[ Hazard Class ]:
9.0
[ HS Code ]:
2927000090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2927000090
[ Summary ]:
2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
Articles
J. Chromatogr. A. 997(1-2) , 87-94, (2003)
The cationic dye, chrysoidine, has been used for the first time as a probe for the indirect photometric detection of cations. The dye has been used as a probe at concentrations of 5 mM, which is rough...
Transcriptional responses in neonate and adultDaphnia magnain relation to relative susceptibility to genotoxicantsAquat. Toxicol. 104(3-4) , 192-204, (2011)
Little information is available on the responses of lower animals to genotoxic chemicals or on their sensitivity for detecting genotoxic chemicals, especially at different life-stages, despite the est...
Development of a highly sensitive and specific immunoassay for determining chrysoidine, a banned dye, in soybean milk film.Molecules 16(8) , 7043-57, (2011)
A highly specific and sensitive indirect competitive enzyme-linked immunosorbent assay (icELISA)was developed for the first time for the detection of chrysoidine, a dye banned in soybean milk film. Tw...