Azaleatin

Names

[ CAS No. ]:
529-51-1

[ Name ]:
Azaleatin

[Synonym ]:
Quercetin 5-methyl ether
3,7,3',4'-tetrahydroxy-5-methoxyflavone
2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-5-methoxychromen-4-one
Azaleatin
5-O-Methyl Quercetin

Biological Activity

[Description]:

Azaleatin is an O-methylated flavonol isolated from Rhododendron species. Azaleatin is a dipeptidyl peptidase-IV inhibitor. Azaleatin can be used for the research of type-2 diabetes and obesity[1][2].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Dipeptidyl Peptidase

Research Areas >> Metabolic Disease

[Target]

Dipeptidyl Peptidase-IV Inhibitor[2]

[References]

[1]. Harborne JB, et, al. Leaf survey of flavonoids and simple phenols in the genus Rhododendron. Phytochemistry. 1971 Nov; 10(11): 2727-2744.

[2]. The medicinal usage of azaleatin. CN107375268A.

Chemical & Physical Properties

[ Density]:
1.634g/cm3

[ Boiling Point ]:
657.3ºC at 760mmHg

[ Molecular Formula ]:
C₁₆H₁₂O₇

[ Molecular Weight ]:
316.26200

[ Flash Point ]:
250.2ºC

[ Exact Mass ]:
316.05800

[ PSA ]:
120.36000

[ LogP ]:
2.29100

[ Index of Refraction ]:
1.74

Safety Information

[ HS Code ]:
2914509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914509090

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%