6-bromo-3-formylchromone

Names

[ Name ]:
6-bromo-3-formylchromone

[Synonym ]:
6-BroMo-3-forMylchroMone
MFCD00191849
6-bromo-4-oxochromene-3-carbaldehyde
6-Bromo-4-oxo-4H-1-benzopyran-3-carboxaldehyde
6-Bromochromone-3-carboxaldehyde

Chemical & Physical Properties

[ Density]:
1.835g/cm3

[ Boiling Point ]:
365.7ºC at 760 mmHg

[ Melting Point ]:
190-193 °C(lit.)

[ Molecular Formula ]:
C₁₀H₅BrO₃

[ Molecular Weight ]:
253.04900

[ Flash Point ]:
175ºC

[ Exact Mass ]:
251.94200

[ PSA ]:
47.28000

[ LogP ]:
2.36800

[ Index of Refraction ]:
1.713

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914700090

Customs

[ HS Code ]: 2914700090

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Articles

Discovery of new chromone containing sulfonamides as potent inhibitors of bovine cytosolic carbonic anhydrase.

Bioorg. Med. Chem. 19 , 3367-71, (2011)

Series of chromone containing sulfonamides were prepared by the reaction of (un)substituted 3-formylchromones with 3-aminobenzenesulfonamide and 4-aminobenzenesulfonamide. Bovine carbonic anhydrase (b...

Multidrug resistance reversal by 3-formylchromones in human colon cancer and human mdr1 gene-transfected mouse lymphoma cells.

In Vivo 20(5) , 645-9, (2006)

Several new 3-formylchromone derivatives proved to be modifiers of multidrug resistance in mouse lymphoma cells and in human Colo320 colon cancer cells. There is apparently a structure-activity relati...

Biological activity of 3-formylchromones and related compounds.

In Vivo 21(5) , 829-34, (2007)

Several 3-formylchromone derivatives were examined for their tumor cell-cytotoxic, anti-Helicobacter pylori, urease inhibitory and anti-HIV activity. Comparing their relative cytotoxicity against four...