MsbA inhibitor 1

Names

[ Name ]:
MsbA inhibitor 1

Biological Activity

[Description]:

MsbA inhibitor 1 is a novel small molecule lipopolysaccharide biogenesis inhibitor, inhibits MsbA, an ATP-dependent flippase that translocates LPS across the inner membrane; causes mislocalization of LPS to the cell interior, inhibits Δ5 strain with MIC of 0.2 ug/ml.

[References]

References 1. Zhang G, et al. Proc Natl Acad Sci U S A. 2018 May 7. pii: 201804670. View Related Products by Target Bacterial

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₄ClNO₃S

[ Molecular Weight ]:
335.802

MsbA inhibitor 1

Names

Biological Activity

Chemical & Physical Properties

Related Compounds