1-Benzyl-2,5-dimethylserotonin hydrochloride
Names
[ CAS No. ]:
525-02-0
[ Name ]:
1-Benzyl-2,5-dimethylserotonin hydrochloride
[Synonym ]:
1-Benzyl-2,5-dimethylserotonin hydrochloride
Benanserin HCl
Benzyl antiserotonin
1-Benzyl-2-methyl-5-methoxytryptamine hydrochloride
Serotonin benzyl analog
Woolley's antiserotonin
Benanserin hydrochloride
Chemical & Physical Properties
[ Boiling Point ]:
494.7ºC at 760 mmHg
[ Molecular Formula ]:
C19H23ClN2O
[ Molecular Weight ]:
330.85200
[ Flash Point ]:
253ºC
[ Exact Mass ]:
330.15000
[ PSA ]:
40.18000
[ LogP ]:
5.01010
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NL4025000
- CHEMICAL NAME :
- Indole, 3-(2-aminoethyl)-1-benzyl-5-methoxy-2-methyl-, monohydrochloride
- CAS REGISTRY NUMBER :
- 525-02-0
- LAST UPDATED :
- 199009
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C19-H22-N2-O.Cl-H
- MOLECULAR WEIGHT :
- 330.89
- WISWESSER LINE NOTATION :
- T56 BNJ B1R& C1 D2Z GO1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 9,819,1966
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 18,833,1963 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 70 mg/kg
- SEX/DURATION :
- female 8-14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - stillbirth Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - behavioral
- REFERENCE :
- PEDIAU Pediatrics. (American Academy of Pediatrics, P.O. Box 1034, Evanston, IL 60204) V.1- 1948- Volume(issue)/page/year: 27,318,1961