Licoricone

Names

[ Name ]:
Licoricone

[Synonym ]:
7-Hydroxy-3-[6-hydroxy-2,4-dimethoxy-3-(3-methyl-2-buten-1-yl)phenyl]-4H-chromen-4-one
7-Hydroxy-3-[6-hydroxy-2,4-dimethoxy-3-(3-methyl-but-2-enyl)-phenyl]-1-benzopyran-4-one
Licoricone
7-hydroxy-3-[6-hydroxy-2,4-dimethoxy-3-(3-methylbut-2-enyl)phenyl]chromen-4-one
4H-1-Benzopyran-4-one, 7-hydroxy-3-[6-hydroxy-2,4-dimethoxy-3-(3-methyl-2-buten-1-yl)phenyl]-

Biological Activity

[Description]:

Licoricone is an flavonoid extracted from licorice, exhibits anti-helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Fukai T, et al. Anti-Helicobacter pylori flavonoids from licorice extract. Life Sci. 2002 Aug 9;71(12):1449-63.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
605.6±55.0 °C at 760 mmHg

[ Melting Point ]:
250-251℃

[ Molecular Formula ]:
C₂₂H₂₂O₆

[ Molecular Weight ]:
382.406

[ Flash Point ]:
212.9±25.0 °C

[ Exact Mass ]:
382.141632

[ PSA ]:
89.13000

[ LogP ]:
5.19

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.615

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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