<Suppliers Price>

stephanine

Names

[ CAS No. ]:
517-63-5

[ Name ]:
stephanine

[Synonym ]:
5H-1,3-Benzodioxolo[6,5,4-de]benzo[g]quinoline, 6,7,7a,8-tetrahydro-9-methoxy-7-methyl-, (7aR)-
(7aR)-9-Methoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinoline
5H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinoline, 6,7,7a,8-tetrahydro-9-methoxy-7-methyl-, (R)-

Biological Activity

[Description]:

Stephanine ((-)-Stephanine) is an isoquinoline aporphine-type alkaloid. Stephanine induce apoptosis through the reverse of mitotic exit. Stephanine exhibits Antiplasmodial activity. Stephanine can be used for the research of stomach pain, abdominal pain, arthritis and cancer[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Research Areas >> Infection
Research Areas >> Inflammation/Immunology

[References]

[1]. Cui L, et, al. The anti-inflammatory and analgesic activities of 2Br-Crebanine and Stephanine from Stephania yunnanenses H. S.Lo. Front Pharmacol. 2023 Jan 4;13:1092583.  

[2]. Le PM, et, al. Stephanine from Stephania venosa (Blume) Spreng Showed Effective Antiplasmodial and Anticancer Activities, the Latter by Inducing Apoptosis through the Reverse of Mitotic Exit. Phytother Res. 2017 Sep;31(9):1357-1368.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
463.6±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H19NO3

[ Molecular Weight ]:
309.36

[ Flash Point ]:
140.4±25.9 °C

[ Exact Mass ]:
309.136505

[ PSA ]:
30.93000

[ LogP ]:
4.16

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.631

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.