solvent green 1

Names

[ CAS No. ]:
510-13-4

[ Name ]:
solvent green 1

[Synonym ]:
Solvent Green 1
EINECS 208-109-7
MFCD00151208
bis[4-(dimethylamino)phenyl]-phenylmethanol

Biological Activity

[Description]:

Malachite Green Carbinol base (MGOH, MGCB) is a derivative of Malachite green (MG) with not fluorescence. Malachite green carbinol base (MGOH, MGCB), as a pH regulation reagent，MGCB molecule could release OH- under UV light irradiation and generate a progressive shift in pH values. MGCB solution turns from colorless to deep green rapidly when exposed to a high-pressure UV lamp (500 W, 50 W/cm)[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Anti-infection >> Fungal

[In Vitro]

Malachite Green Carbinol base (MGOH, MGCB), a triphenylmethane leucohydroxide derivative, is used as a light-induced hydroxide ion emitter. Used for dyeing silk, wool, jute, leather, and cotton. Also used as a biological stain and fungicide/parasiticide for fish[1][2]

[References]

[1]. Yubin Zhou, et al. Organic additives stabilize RNA aptamer binding of malachite green. Talanta. 2016 Nov 1;160:172-182. https://pubmed.ncbi.nlm.nih.gov/27591602/

[2]. Can Xu, et al. Versatile Dual Photoresponsive System for Precise Control of Chemical Reactions. ACS Nano. 2017 Aug 22;11(8):7770-7780.

Chemical & Physical Properties

[ Density]:
1.131g/cm3

[ Boiling Point ]:
526.2ºC at 760mmHg

[ Melting Point ]:
112-114ºC

[ Molecular Formula ]:
C₂₃H₂₆N₂O

[ Molecular Weight ]:
346.46500

[ Flash Point ]:
268.2ºC

[ Exact Mass ]:
346.20500

[ PSA ]:
26.71000

[ LogP ]:
4.10280

[ Index of Refraction ]:
1.635

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DN8600000

CHEMICAL NAME :: Benzyl alcohol, alpha,alpha-bis(p-dimethylaminophenyl)-

CAS REGISTRY NUMBER :: 510-13-4

BEILSTEIN REFERENCE NO. :: 2222125

LAST UPDATED :: 199709

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C23-H26-N2-O

MOLECULAR WEIGHT :: 346.51

WISWESSER LINE NOTATION :: 1N1&R DXQR&R DN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 470 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 1,5,1951

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 1,5,1951

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
N-Xn

[ Risk Phrases ]:
R63

[ Safety Phrases ]:
S61

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DN8600000

[ HS Code ]:
2922199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%