4-Fluoro-L-phenylalanine

Names

[ CAS No. ]:
51-65-0

[ Name ]:
4-Fluoro-L-phenylalanine

[Synonym ]:
EINECS 200-113-7
p-Fluoro-DL-phenylalanine
S-(-)-p-Fluorophenylalanine
para-fluorophenylalanine
4-Fluorophenylalanine
DL-4-Fluorophenylalanine
4-Fluoro-DL-.β.-phenylalanine
L-4-Fluorophenylalanine
p-Fluoro-L-phenylalanine
L-4-Fluoro-Phenylalanine
(2S)-2-amino-3-(4-fluorophenyl)propanoic acid
2-Amino-3-(4-fluorophenyl)propanoic acid
Phenylalanine, 4-fluoro-
2-Amino-3-(4-fluorophenyl)propionic Acid
H-DL-Phe(4-F)-OH
4-Fluoro-DL-phenylalanine
para-fluoro-l-phenylalanine
MFCD00002600
(S)-2-Amino-3-(4-fluorophenyl)propanoic acid

Biological Activity

[Description]:

2-Amino-3-(4-fluorophenyl)propanoic acid is a phenylalanine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-814.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
313.3±32.0 °C at 760 mmHg

[ Melting Point ]:
253-255ºC

[ Molecular Formula ]:
C₉H₁₀FNO₂

[ Molecular Weight ]:
183.180

[ Flash Point ]:
143.3±25.1 °C

[ Exact Mass ]:
183.069550

[ PSA ]:
63.32000

[ LogP ]:
1.16

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.555

[ Stability ]:
Stable. Combustible. Incompatible with strong oxidising agents. May be light sensitive.

[ Water Solubility ]:
slightly soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AY6315000

CHEMICAL NAME :: Alanine, 3-(p-fluorophenyl)-, DL-

CAS REGISTRY NUMBER :: 51-65-0

LAST UPDATED :: 199701

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C9-H10-F-N-O2

MOLECULAR WEIGHT :: 183.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Rodent - rabbit Kidney

DOSE/DURATION :: 500 umol/L

REFERENCE :: ECREAL Experimental Cell Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.10- 1950- Volume(issue)/page/year: 36,92,1964

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300

[ Precautionary Statements ]:
P264-P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic;

[ Risk Phrases ]:
R25

[ Safety Phrases ]:
S45

[ RIDADR ]:
UN 2811

[ WGK Germany ]:
3

[ RTECS ]:
AY6315000

[ Packaging Group ]:
III

[ HS Code ]:
2922499990

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

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