5'-(N-Cyclopropyl)carboxamidoadenosine

Names

[ CAS No. ]:
50908-62-8

[ Name ]:
5'-(N-Cyclopropyl)carboxamidoadenosine

[Synonym ]:
NCPCA
5'-N-Cyclopropylcarboxamide adenosine
CPCA
MFCD00055130
5'-N-cyclopropyl-carboxyamidoadenosine

Biological Activity

[Description]:

5'-(N-Cyclopropyl)carboxamidoadenosine (CPCA) is an adenosine A2 receptor agonist[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor

[References]

[1]. J Malhotra, et al. Effect of adenosine receptor modulation on pentylenetetrazole-induced seizures in rats. Br J Pharmacol. 1997 Jan;120(2):282-8.

Chemical & Physical Properties

[ Density]:
2.09g/cm3

[ Molecular Formula ]:
C₁₃H₁₆N₆O₄

[ Molecular Weight ]:
320.30400

[ Exact Mass ]:
320.12300

[ PSA ]:
148.41000

[ Index of Refraction ]:
1.961

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VJ2223500

CHEMICAL NAME :: Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-N-cyclopropyl-1-deoxy-

CAS REGISTRY NUMBER :: 50908-62-8

LAST UPDATED :: 199007

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C13-H16-N6-O4

MOLECULAR WEIGHT :: 320.35

WISWESSER LINE NOTATION :: T56 BN DN FN HNJ IZ D- BT5OTJ CQ DQ EVM- AL3TJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,313,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,313,1980

Safety Information

[ Hazard Codes ]:
T+

[ Risk Phrases ]:
26/27/28

[ Safety Phrases ]:
S22;S45;S36/S37/S39

[ RIDADR ]:
UN 2811 6.1/PG 1

[ Hazard Class ]:
6.1(a)

Precursor & DownStream

Precursor

DownStream

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.