NY-ESO-1 (87-111)

Names

[ Name ]:
NY-ESO-1 (87-111)

Biological Activity

[Description]:

NY-ESO-1 (87-111) is a pan-MHC class II-restricted peptide sequence. NY-ESO-1 (87-111) binds to multiple HLA-DR and HLA-DP4 molecules, and stimulates Th1-type and Th-2/Th0-type CD4+ T cells when presented in the context of HLA-DR and HLA-DP4 molecules[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Maja Mandic, et al. One NY-ESO-1-derived epitope that promiscuously binds to multiple HLA-DR and HLA-DP4 molecules and stimulates autologous CD4+ T cells from patients with NY-ESO-1-expressing melanoma. J Immunol. 2005 Feb 1;174(3):1751-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₃₁H₂₀₆N₃₂O₃₆S₂

[ Molecular Weight ]:
2869.40

Related Compounds

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