Methotrexate di-n-butyl ester
Names
[ CAS No. ]:
50602-77-2
[ Name ]:
Methotrexate di-n-butyl ester
[Synonym ]:
Dbmtx
dibutyl n-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)glutamate
Glutamic acid,N-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-,dibutyl ester,L-(+)
Dibutyl methotrexate
2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoyl}-glutamic acid dibutyl ester
Methotrexate di-n-butyl ester
Chemical & Physical Properties
[ Density]:
1.272g/cm3
[ Molecular Formula ]:
C28H38N8O5
[ Molecular Weight ]:
566.65200
[ Exact Mass ]:
566.29700
[ PSA ]:
188.54000
[ LogP ]:
4.33910
[ Index of Refraction ]:
1.619
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MA1230000
- CHEMICAL NAME :
- Glutamic acid, N-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)b enzoyl)-, dibutyl ester, L-(+)-
- CAS REGISTRY NUMBER :
- 50602-77-2
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C28-H38-N8-O5
- MOLECULAR WEIGHT :
- 566.74
- WISWESSER LINE NOTATION :
- T66 BN DN GN JNJ CZ EZ H1N1&R DVMYVO4&2VO4
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - mouse Leukocyte
- DOSE/DURATION :
- 1 umol/L
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 25,1943,1976