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Ethyl (5Z,9Z,12Z)-5,9,12-octadecatrienoate

Names

[ CAS No. ]:
493015-74-0

[ Name ]:
Ethyl (5Z,9Z,12Z)-5,9,12-octadecatrienoate

[Synonym ]:
Ethyl (5Z,9Z,12Z)-5,9,12-octadecatrienoate
ethyl 5Z,9Z,12Z-octadecatrienoate
5,9,12-Octadecatrienoic acid, ethyl ester, (5Z,9Z,12Z)-
ethyl pinolenate
pinolenic acid ethyl ester

Biological Activity

[Description]:

Pinolenic acid is a polyunsaturated fatty acid found in the seed oils of red pine (Pinus orientalis) and maritime pine (Pinus pinaster). Both oils were found to have lipid-lowering properties. A diet containing marine pine nut oil (MPSO) reduces HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to reduce cholesterol efflux in vitro. Korean pine nut oil supplements may help obesity by reducing appetite. People who take this oil experience an increase in the satiety hormones CCK and GLP-1 and a decrease in appetite. The activity of the oil is attributed to pinolenic acid. Pinolenic acid is not metabolized to arachidonic acid and can reduce the level of arachidonic acid in the phosphatidylinositol fraction of HepG2 cells from 15.9% to 7.0%. Pinolenic acid ethyl ester is a neutral, more lipophilic form of the free acid.

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
390.6±31.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H34O2

[ Molecular Weight ]:
306.483

[ Flash Point ]:
100.8±23.2 °C

[ Exact Mass ]:
306.255890

[ PSA ]:
26.30000

[ LogP ]:
7.65

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.475

Related Compounds