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Dehydroemetine

Names

[ CAS No. ]:
4914-30-1

[ Name ]:
Dehydroemetine

[Synonym ]:
Dehydroemetinum
Dehidroemetina
2,3-didehydro-emetine
2,3-Didehydroemetin
Emetine,2,3-didehydro
10,11,6',7'-tetramethoxy-emet-2-ene
Mebadin
dehydroemetine
BT 436
2-Dehydroemetine
(-)-2,3-Dehydroemetine

Biological Activity

[Description]:

Dehydroemetine, a synthetic analogue of emetine dihydrochloride, is used for visceral leishmaniasis. Dehydroemetine used for anti-parasites[1].

[Related Catalog]:

Research Areas >> Infection

[References]

[1]. Fouarge M, et al.Development of dehydroemetine nanoparticles for the treatment of visceral leishmaniasis.J Microencapsul. 1989 Jan-Mar;6(1):29-34.

Chemical & Physical Properties

[ Density]:
1.19g/cm3

[ Boiling Point ]:
604.7ºC at 760mmHg

[ Melting Point ]:
94-96°

[ Molecular Formula ]:
C29H38N2O4

[ Molecular Weight ]:
478.62300

[ Flash Point ]:
319.5ºC

[ Exact Mass ]:
478.28300

[ PSA ]:
52.19000

[ LogP ]:
5.27430

[ Index of Refraction ]:
1.606

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JY5095000
CHEMICAL NAME :
Emetine, 2,3-didehydro-
CAS REGISTRY NUMBER :
4914-30-1
LAST UPDATED :
199410
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C29-H38-N2-O4
MOLECULAR WEIGHT :
478.69

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
68800 ug/kg/24H (Continuous)
REFERENCE :
IMSCE2 IRCS Medical Science. (Lancaster, UK) V.12-14, 1984-86. For publisher information, see MSCREJ. Volume(issue)/page/year: 13,946,1985

Related Compounds

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