Thermopsine

Names

[ CAS No. ]:
486-90-8

[ Name ]:
Thermopsine

[Synonym ]:
l-Thermopsine
7,14-Methano-2H,11H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-11-one, 1,3,4,6,7,13,14,14a-octahydro-
thermospine
(-)-Anagyrine
(-)-thermopsine
7,14-Methano-2H,11H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-11-one,1,3,4,6,7,13,14,14a-octahydro-,(7R,14R,14aS)
(7α,9α)-3,4,5,6-Tetradehydrospartein-2-one
3,4,5,6-Tetradehydrospartein-2-one
(7R,14R,14aS)-1,3,4,6,7,13,14,14a-Octahydro-7,14-methano-2H,11H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-11-one
Thermopsine
(-)-Thermopsin
7,14-Methano-2H,11H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-11-one, 1,3,4,6,7,13,14,14a-octahydro-, (7R,14R,14aS)-

Biological Activity

[Description]:

Thermopsine is a quinolizidine alkaloid isolated from the fruits and pods and stem bark of Sophora velutina subsp. Thermopsine has antibacterial activity[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Korir E, et al. Quinolizidine alkaloids from Sophora velutina subsp. zimbabweensis (Fabaceae: Sophoreae). Nat Prod Commun. 2012 Aug;7(8):999-1003.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
455.6±34.0 °C at 760 mmHg

[ Melting Point ]:
205-206ºC

[ Molecular Formula ]:
C₁₅H₂₀N₂O

[ Molecular Weight ]:
244.332

[ Flash Point ]:
216.3±18.0 °C

[ Exact Mass ]:
244.157562

[ PSA ]:
25.24000

[ LogP ]:
1.65

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.628

Related Compounds

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