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m-PEG5-2-methylacrylate

Names

[ CAS No. ]:
48074-75-5

[ Name ]:
m-PEG5-2-methylacrylate

Biological Activity

[Description]:

m-PEG5-2-methylacrylate is a PEG- and Alkyl/ester-based PROTAC linker can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

Alkyl/ether


[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. Yong Ku Kwon,et al. Reduced excimer formation in polyfluorenes by introducing coil-like poly[penta(ethylene glycol) methyl ether methacrylate] block segments. Macromolecules, 2009, 42(3), 887-891.

Chemical & Physical Properties

[ Molecular Formula ]:
C15H28O7

[ Molecular Weight ]:
320.38

Related Compounds