CORM-3

Names

[ Name ]:
CORM-3

[Synonym ]:
MFCD07364048

Biological Activity

[Description]:

CORM-3, a water-soluble carbon monoxide-releasing molecule, attenuates NF-κB p65 nuclear translocation, reduces ROS generation and enhances intracellular glutathione and superoxide dismutase levels[1][2][3].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[References]

[1]. Foresti R, et al. Vasoactive properties of CORM-3, a novel water-soluble carbon monoxide-releasing molecule. Br J Pharmacol. 2004 Jun;142(3):453-60.

[2]. Lee DW, et al. Carbon monoxide regulates glycolysis-dependent NLRP3 inflammasome activation in macrophages. Biochem Biophys Res Commun. 2017 Nov 18;493(2):957-963.

[3]. Huang Y, et al. Carbon monoxide (CO) inhibits hydrogen peroxide (H2O2)-induced oxidative stress and the activation of NF-κB signaling in lens epithelial cells. Exp Eye Res. 2018 Jan;166:29-39.

Chemical & Physical Properties

[ Molecular Formula ]:
C₅H₄ClNO₅Ru

[ Molecular Weight ]:
296.62800

[ Exact Mass ]:
296.89800

[ PSA ]:
112.85000

[ Storage condition ]:
-20℃

Safety Information

[ Hazard Codes ]:
N

[ RIDADR ]:
NONH for all modes of transport

Related Compounds

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