Acetyl-(N-Me-Leu17,N-Me-Phe19)-Amyloid β-Protein (16-20) amide trifluoroacetate salt

Names

[ CAS No. ]:
461640-33-5

[ Name ]:
Acetyl-(N-Me-Leu17,N-Me-Phe19)-Amyloid β-Protein (16-20) amide trifluoroacetate salt

[Synonym ]:
A|A16-20m
Ac-Lys-(Me)Leu-Val-(Me)Phe-Phe-NH2 trifluoroacetate salt

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₁H₆₀F₃N₇O₈

[ Molecular Weight ]:
835.95200

[ Exact Mass ]:
835.44600

[ PSA ]:
245.79000

[ LogP ]:
6.92070

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Design and characterization of a membrane permeable N-methyl amino acid-containing peptide that inhibits Abeta1-40 fibrillogenesis.

J. Pept. Res. 60 , 37-55, (2002)

Alzheimer's disease, Huntington's disease and prion diseases are part of a growing list of diseases associated with formation of beta-sheet containing fibrils. In a previous publication, we demonstrat...

Probing the role of backbone hydrogen bonding in beta-amyloid fibrils with inhibitor peptides containing ester bonds at alternate positions.

Biochemistry 42 , 475-485, (2003)

Protein-protein interactions are frequently mediated by stable, intermolecular beta-sheets. A number of cytokines and the HIV Protease, for example, dimerize through beta-sheet motifs. Evidence also s...