(S) 93-31

Names

[ Name ]:
(S) 93-31

Biological Activity

[Description]:

A pH-dependent, GluN2B-selective inhibitor of NMDA receptor with IC50 of 0.19 uM at pH6.9, 10-fold selecivity over brain tissue pH 7.6 (IC50=1.8 uM); maximizes neuroprotection in ischemic tissue while minimizing on-target side effects associated with NMDAR blockade in noninjured brain regions.

[References]

References 1. Yuan H, et al. Neuron. 2015 Mar 18;85(6):1305-1318. View Related Products by Target iGluR

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₃₀Cl₂N₂O₄S

[ Molecular Weight ]:
489.452

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.